PREFACE
Preface
In recent years, the field of pharmaceutical sciences has seen remarkable advancements in drug delivery systems. Among these innovations, the development of emulgels, microemulgels, nanoemulgels, niosomes, and exosomes has opened new horizons for effective and targeted drug delivery. This book provides a comprehensive overview of these cutting-edge carrier systems, highlighting their potential applications, benefits, and future prospects.
One of the key challenges in the evolving landscape of pharmaceutical sciences is the formulation and delivery of poorly water-soluble drugs. Self-Emulsifying Drug Delivery Systems (SEDDS) have emerged as a promising solution to enhance the bioavailability of these drugs. This innovative approach utilizes the unique properties of self-emulsifying formulations to improve the absorption and efficacy of therapeutic compounds. This book aims to provide a thorough examination of SEDDS, exploring their mechanisms, formulation strategies, and potential applications in modern medicine. By delving into the intricacies of SEDDS, we hope to shed light on their transformative potential and the future directions of drug delivery research.
Emulgels, microemulgels, and nanoemulgels represent an exciting blend of emulsions and gels, combining the advantages of both systems. These formulations offer improved bioavailability, controlled release, and enhanced stability, making them suitable for a variety of therapeutic applications. In this book, we explore the formulation, characterization, and evaluation of these emulgel-based systems, providing valuable insights into their unique properties and potential uses.
Niosomes, another cutting-edge carrier system, have garnered significant attention due to their ability to encapsulate both hydrophilic and lipophilic drugs. As non-ionic surfactant vesicles, niosomes offer several advantages, including biocompatibility, improved drug stability, and controlled release. This book examines the formulation techniques, physicochemical properties, and therapeutic applications of niosomes, highlighting their versatility and effectiveness.
The secretome, particularly in the form of exosomes, has emerged as a promising cell-free carrier system. Exosomes, nanometer-sized extracellular vesicles, play a crucial role in intercellular communication and hold great potential for drug delivery and regenerative medicine. This book provides an in-depth analysis of the secretome, focusing on the isolation, characterization, and therapeutic applications of exosomes, emphasizing their role as natural and efficient drug carriers.
Through a detailed exploration of these advanced carrier systems, this book aims to bridge the gap between research and clinical practice. It offers valuable insights for scientists, researchers, and healthcare professionals. The chapters, authored by leading experts in the field, ensure a thorough and up-to-date understanding of the topics covered.
We hope that this book serves as a valuable resource, inspiring further research and innovation in the field of drug delivery systems. As we continue to explore the potential of self-emulsifying drug delivery systems, emulgels, niosomes, secretomes, and exosomes, we move closer to realizing more effective, targeted, and personalized therapies for a wide range of diseases.
Sincerely,
Prof. Dr. Emel Öykü Çetin Uyanıkgil
İzmir, Türkiye
02.07.2024
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